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Red blood cells (erythrocytes). Blood groups

Red blood cells (erythrocytes). Blood groups

The membrane of the red cell has on its surface a group of molecules that confer blood groupspecificity (i.e., that differentiate blood cells into groups). Most blood group substances are composed of carbohydrate linked to protein, and it is usually the chemical structure of the carbohydrate portion that determines the specific blood type. Blood group substances are antigens capable of inducing the production of antibodies when injected into persons or animals lacking the antigen. Detection and recognition of the blood group antigens are accomplished by the use of serum containing these antibodies. The large number of different red cell antigens makes it extremely unlikely that persons other than identical twins will havethe same array of blood group substances. (For a full treatment of the subject, see blood groups.)

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